The New England Journal of Medicine has published a clinical image case highlighting flushing as a key visible symptom of carcinoid syndrome, a condition caused by hormone-secreting tumours.
The New England Journal of Medicine posted the case to its social media channels, tagging it under oncology and endocrinology — the two specialties most likely to encounter the condition.
Carcinoid syndrome occurs when a type of slow-growing tumour called a neuroendocrine tumour (NET) releases hormones, above all serotonin, directly into the bloodstream. The most visible and often earliest symptom is flushing — a sudden reddening or warmth of the face, neck, and upper chest that can look like a blush but lasts longer and returns repeatedly.
It’s easy to dismiss. Many people put flushing down to anxiety, menopause, or alcohol. But when it keeps coming back without an obvious trigger, it can be worth raising with a GP.
According to the NHS, other symptoms associated with carcinoid syndrome can include diarrhoea, wheezing, and a rapid heartbeat. The condition is rare, and symptoms often develop gradually, which means diagnosis can take time.
Neuroendocrine tumours most commonly start in the digestive system or lungs. The NHS notes that they are generally slow-growing compared with other cancers, though they do vary in behaviour.
If you’re experiencing repeated, unexplained flushing alongside any of the other symptoms listed above, speak to your GP. They can arrange blood and urine tests that check for hormone levels associated with the condition. Do not use this article as a basis for self-diagnosis — only a clinician can assess your symptoms properly.
For general health concerns, NHS 111 is available by phone or online around the clock.
Source: @NEJM